Ankylosing spondylitis is a seropositive spondyloarthropathy, and rheumatoid arthritis are two completely different diseases, the clinical evidence of the disease, the main location of the disease is involved in the patient’s sacroiliac joints and spine, the pre-type patients have more lumbar hip pain, stiffness. In the case of prolonged disease, the spine is straight and deformed, and the spine shows bamboo-like changes on X-ray, and the hip joint is destroyed and straightened. Western medicine has so far mostly used anti-inflammatory pain, POTEXON and other western drugs to relieve symptoms, or with a fixed Chinese medicine formula treatment, although there is a recent effect, but easy to relapse after stopping the drug, and long-term use of painkillers easy to damage the gastrointestinal tract, causing gastric bleeding, long-term painkillers will also become addicted, extremely harmful. The rheumatology department of Nantong City Hospital Wu Jian a. The understanding of the etiology of ankylosing spondylitis ankylosing spondylitis, belongs to the Chinese medicine “kidney paralysis”, “bone paralysis” category. Professor Zhu Liangchun divided it into two types of treatment: pre-existing “kidney paralysis type” and long-standing “bone paralysis type”. Ankylosing spondylitis is characterized by prolonged pain and stasis, prolonged pain into the ligaments, prolonged disease and deficiency, and prolonged disease and kidney. The patient has a deficiency of yang energy, so the evil attacked the meridians, wind, cold, moisture and heat invasion of the evil, Qi and blood for the evil blocked, congestion of the meridians, stagnation in the internal, wet stop for phlegm, blood clotting for stasis, phlegm and stasis, clotting not kidney paralysis, wet and heat blocked type pass, deep bone and joint, stuck, confusion of evil, such as oil into the face, swelling and pain, so quite tricky, not easy to quick results. If the five body paralysis is not cured for a long time and involves the internal organs, it can turn into five organ paralysis. We have realized through long-term practice that this evidence is not cured for a long time, both the positive side of the deficiency and the evil side of the real; and the lesion is in the bone, the bone is the master of the kidney, and the supervisory vein supervises all the veins of the body, so we establish the treatment principle of benefitting the kidney and strengthening the supervisory vein to treat its root, and releasing the paralysis and opening the luo to treat its symptoms. The first is that the patient’s body is not in a position to be able to use the body for the purpose of treatment. The pain gradually moves up to the lumbar back and is fixed, and can also affect the thoracic spine and neck. Aversion to cold, stiffness, at night or in the early morning, hands and feet are not warm, the pain is slowed by warmth, legs and knees are sore and soft, or even spinal deformity, difficulty in movement, light tongue with purple gas, thin white moss, sunken string pulse. Treatment: Benefit the kidneys and warm the yang, resolve blood stasis and clear the Governor. Prescription: 30-60 g of Andrographis paniculata, 30 g each of Bonesetter, Nansheng, Gynostemma, Wailingxian, 15 g each of Deerbit, Epimedium, Cistanches, 10 g each of Angelica, Silkworm, Ground turtle worm, Ocimum sanctum, 6 g of Glycyrrhiza glabra. 1 dose daily, decoction in water, divided into 2 doses, for 6-12 months. This formula has the effect of dispelling wind-dampness, clearing meridians, activating blood circulation and resolving blood stasis. Add and subtract according to the symptoms: if the tongue is pale and the side teeth are heavy, increase the amount of Astragalus to 60-100g; if it is cold, add 10g each of Chuan Wu and Gui Zhi, or 10-15g of Radix et Rhizoma Pseudostellariae, and 3g of dried ginger; if it is phlegm, add 15g of fried white mustard seeds and 10-15g of ginger and half asia; if it is painful, add 30g of raw white peony and 15g of elderberry; if the blood sedimentation and C-reactive protein are significantly elevated, add 30g each of Ginseng and Radix et Rhizoma Pseudostellariae. 2. Yin deficiency pulse paralysis type. The symptoms include pain in the lumbar spine, thoracic vertebrae and neck, stiffness is more intense, bending, turning over, squatting, turning the neck and other activities are limited, thin, fatigue, body baking and dry mouth, heat in the heart of the hands and feet, and even irritability and sleeplessness, serious deformity of the spine, pain is fixed, light day and night, red tongue or dark tongue with petechiae, thin moss or thin yellow moss, thin string and astringent pulse. Treatment: Benefit the kidney and nourish yin, and regulate the Governor’s vein. Prescription: 30-60 g of Andrographis paniculata, 10-15 g each of Radix Rehmanniae Praeparata and Turtle A, 10 g of Radix et Rhizoma Ligustrum, 15 g of Radix et Rhizoma Mulberry, 30 g each of Radix et Rhizoma Bone, 15 g of Radix et Rhizoma Sulcatae, 10 g of Radix et Rhizoma Bone, 6 g of Radix et Rhizoma Glycyrrhiza Uralensis. Add and subtract according to the symptoms: add 10g of Agaricus blazei and 30g of Gynostemma spp. for blood deficiency; add 15-20g of Radix et Rhizoma tigrinum and 15g of Radix gentianae.