Ankylosing spondylitis (AS) is a chronic progressive inflammatory disease that primarily affects the spine and can involve the sacroiliac and peripheral joints to varying degrees. The disease is also known as Marie-strümpell disease, Von Bechterew disease, rheumatoid spondylitis, deforming spondylitis, rheumatoid central type, etc. AS is characterized by inflammation and ossification of the spinal joints and ligaments of the lumbar, cervical, and thoracic segments, as well as the sacroiliac joints, often involving the hip joint, and other peripheral joints may also be inflamed. The disease is generally rheumatoid factor negative, so it is collectively seronegative spondylosis with Reiter’s syndrome, psoriatic arthritis, and enteropathic arthritis. 1, ankylosing spondylitis is a lingering disease, many patients with ankylosing spondylitis in the treatment process there is impatience, lack of adequate mental preparation to adhere to long-term treatment, the mood becomes very pessimistic, lose confidence to give up treatment, is very dangerous. Must overcome impatience, treatment in a timely and appropriate manner, to build up confidence to overcome the disease. 2, pay attention to maintain the physiological posture to prevent the occurrence of spinal deformity and stiffness. When resting to maintain the appropriate position, should sleep on a hard bed, take the supine position, no pillows; in standing or sitting position, should try to raise the chest and tuck in the abdomen; when writing the table should be higher, the chair should be shorter. Any physical activity that can cause persistent pain should be avoided. 3, due to pain long-term bedridden patients with ankylosing spondylitis, the spine and limbs ankylosis faster, due to cause in addition to the serious systemic symptoms, pain is obvious, should try to move the joints, adhere to the chest expansion, deep breathing, spinal and lower limb exercises and other local and systemic functional exercises to prevent and reduce joint adhesions, stiffness and muscle atrophy. The ankylosing spondylitis patients who cannot get up because of the seriousness of the disease will be controlled by the medication, you can do some appropriate functional exercises in bed, and strive to get off the ground as soon as possible. 4, in the recovery period is to pay attention to functional calcination such as: bar, backward walking, squatting, bending, do what you can calcine, but pay attention to the proportion, appropriate to stop, not excessive, especially the bar. 5, because of the high chance of hereditary ankylosing spondylitis, it is advisable not to have children before they are cured, and to consider the issue of children only after a few years of treatment without relapse. 6, ankylosing spondylitis patients should pay attention to dietary habits, eat more Yin cool blood food such as: walnuts, peanuts, eggs, green beans, dates, fish, meat, dairy products, etc., less high heat spicy food such as: hot pot, mutton, chili, rabbit, dog, alcohol, etc. 7, ankylosing spondylitis patients should be moderate sex life, in the active period it is best not to have sex, control the disease can be increased after the appropriate number of times. 8, do not sleep on the floor, fan the air conditioning, take a cold shower, do not strain, angry.