Syphilis is a highly contagious sexual disease, usually transmitted through sexual intercourse, many patients suffer from syphilis because of unclean sex, in society people have a certain discrimination for syphilis patients, so suffering from syphilis will not only cause physical pain, but also bring psychological trauma. The danger of syphilis is very great, many families are on the verge of breaking up because of syphilis, so the treatment of syphilis is also very important, syphilis has now been listed as a category B prevention and management of the disease, so it is very harmful. The time of onset of syphilis varies from person to person, generally speaking, the weaker people will have an earlier onset, usually within 2-4 weeks of infection, syphilis patients are generally infected with the virus after 10-90 days or so symptoms, better health, people with other STD pre-treatment, the symptoms of a longer time, but as long as the infection is syphilis, the symptoms are certain. The hard chancre is found within 2-4 weeks of infection with syphilis virus, mostly in the genital area, in the coronal groove, penis and foreskin in men, and in the labia or uterus in women, and is initially expressed as a papule, which quickly breaks down into a small red ulcer, round in shape, with a small amount of plasma discharge, containing a large number of syphilis spirochetes. The chancre is usually solitary and hard like cartilage, but is not painful. The syphilis spirochete enters the bloodstream from the lymph nodes and spreads rapidly through the body, spreading to all parts of the body and causing systemic disease. The rash is coppery red in color, with a small amount of scales adhering to it, often symmetrically distributed and dense without fusion. The onset of syphilis is uncertain and there are many reasons for the onset of syphilis, so the early symptoms of syphilis cannot be determined according to the time, the onset of syphilis will not only invade the mucous membranes, but can also involve all tissues of the body, the destructive nature is very huge, so syphilis is a malignant infectious disease, can not be ignored, should be It should be treated in hospital as soon as possible.