Patients with depression may experience weight loss and other symptoms of wasting. In addition to depression, depressed patients show symptoms such as depressed mood, unhappiness, depression, slower thinking response, reduced thinking content and association way, etc. They also show symptoms such as poorer sleep, difficulty in sleeping, early awakening, weight loss, especially depressed patients have weight loss close to 5%, so some depressed patients will show weight loss as the main symptom. Patients show no appetite, eating tastes like chewing wax, no feeling for food, think eating is a daily task, whenever in the process of eating there is always a painful experience, patients have no desire to eat, but family members still ask them to eat, so it is very painful inside, and after eating food shows gastrointestinal discomfort and other manifestations, will also cause patients to lose weight. Therefore, it is very meaningful to carry out systematic and standardized drug treatment as early as possible and as soon as possible to improve the patient’s eating status.