The liver is the largest gland and the largest substantial organ in the human body. The liver is mainly located in the right quadrant of the rib cage and the upper abdomen. The weight of the liver in our adults is 1230-1450g for men and 1100-1300g for women, accounting for about 1/40 to 1/50 of body weight. In fetuses and newborns, the liver is relatively large, up to 1/20 of body weight. The liver is rich in blood supply, so it is brownish-red in color and soft and brittle in texture. The liver is rounded and thick at the right end and narrow and wedge-shaped at the left end, with two sides, upper and lower, and four edges, front and back. The upper part of the liver is convex against the diaphragm and is divided by the sickle ligament into the left and right lobes; the lower part is slightly concave and adjacent to the nearby organs, with a slightly H-shaped left and right longitudinal sulcus and transverse sulcus on this side. The transverse sulcus contains the portal vein, hepatic artery, hepatic ducts, nerves and lymphatic vessels called the hepatic portal. The majority of the liver is located in the right quadrant and epigastrium, with a small portion in the left quadrant. The upper border of the liver coincides with the dome of the diaphragm.