Penile cancer is a malignant tumor that grows on the male penis, originating from the head, coronal sulcus and mucosa of the inner foreskin and penile skin. The cause of penile cancer is not clear, but it is mainly related to genetic factors, environmental factors or carcinogenic factors. At the early stage of the disease, there are no obvious symptoms of penile cancer, firstly, a hard node will appear on the covered penile head and the patient will feel itchy and tingling, and then a purulent discharge with blood will come out from the urethra. This tumor will continue to expand and penetrate the foreskin, and all the tumor will be exposed, then there will be a foul smell. When the tumor metastasizes extensively, the patient will show signs of general disease such as anemia and emaciation. Penile cancer is very closely related to male circumcision and prepuce. If men with prepuce and excessive prepuce do not pay attention to personal hygiene, the post-circumcision (scale) will stimulate the glans skin for a long time, so the chance of developing penile cancer will be higher than other people. In addition, one of the early signs of penile cancer is the appearance of red spots, papules or lumps in the coronal groove or foreskin. Therefore, it is important to pay attention when these symptoms appear. Men should develop good hygiene habits in general, and those who have long foreskin should be circumcised in time. Do not engage in impure sexual behavior, and discover abnormalities in the penis need to be treated in a timely manner.