Prostate disease is a major disease that affects men’s health. Its most common are prostate hyperplasia, prostatitis, prostate prostate cysts, prostate calcification and stones, prostate cancer, prostate mucus cancer and so on. From the point of view of men’s health, all of these diseases are closely related to sexual dysfunction, which is a major concern for men. Many epidemiologic studies in recent years have confirmed the close relationship between BPH and lower urinary tract symptoms (symptoms of bladder irritation and bladder obstruction) and sexual function, including erectile dysfunction (ED), ejaculatory dysfunction (EjD), decreased ejaculate volume, and painful ejaculation. A study in the United States and Europe showed that 49% of men aged 50-80 years with lower urinary tract symptoms had comorbid ED. lower urinary tract symptoms were the strongest risk factor for ED compared with diabetes mellitus, hypertension, and heart disease. Several national and international studies have demonstrated significant correlations between the baseline prostate symptom index and various aspects of sexual function, including libido, erectile function, ejaculation status, and total satisfaction with sexual intercourse; maximum urinary flow rate is also correlated with male sexual function. Patients with BPH often have a combination of inflammation of the prostate or obstruction of the ejaculatory ducts, which may be the main cause of painful or uncomfortable ejaculation. In addition, the above problems may also be caused by hypogonadism in older men, which reduces the production of androgen-dependent seminal vesicle fluid and significantly reduces semen volume. It has also been shown that there is a common pathophysiological basis between prostate disease and sexual dysfunction in men: it may be caused by a multifactorial combination of reduced release of nitric oxide synthase (NOS)/nitric oxide (NO), and the expression of Rho-kinase, which regulates the contraction signaling pathway of penile cavernous smooth muscle cells.