Duodenal ulcer gastric erosion in the clinical application of drug therapy, including the following categories: 1, for gastrointestinal function power deficiency tract. Morpholine gel as well as total gastrointestinal motility drugs, cisapride tablets can be selected. 2. Proton pump inhibitors can be selected to inhibit the production of gastric acid and reduce symptoms. The drugs clinically used are omeprazole, pantoprazole and lansoprazole. 3. Anti-Helicobacter pylori drugs can also be selected, clinically used penicillin, metronidazole and clarithromycin, etc. 4. Drugs that protect the gastric mucosa can be applied at the same time, including metsulin, aluminum thioglycollate and bismuth pectin, etc. Patients with duodenal ulcer and gastric erosion need to pay attention to their diet during the application of drugs, especially to avoid spicy and irritating food, and should be based on low salt, low fat, low cholesterol food, which is more conducive to increasing nutrition, repairing the ulcer mucosa, and increasing the barrier of the gastrointestinal mucosa are beneficial.