Misconception 1: Most of the poisoned patients who took or contacted paraquat are from rural areas, they do not know the toxicity of paraquat, and they mistakenly think that the herbicide is weak, or they think that the herbicide has no toxic effect on human. The lethal dose of paraquat is 20-40mg/Kg, that is to say, the concentration of 20% aqueous paraquat can kill a person with 5-15ml. The lethal dose for children is 2-5ml of paraquat in water with 20% concentration. In this regard, relevant departments should strengthen the publicity so that farmers can really understand how toxic paraquat is to humans. When spraying pesticides, you should also pay attention to protection, wear rubber gloves and masks, and wear overalls, otherwise paraquat will enter your body through your skin. After spraying, you should change your clothes. If the liquid splashes on your skin or in your eyes, you should rinse with water for 10-15 minutes immediately. There are reports of death by poisoning due to inattention to protection when spraying paraquat. Note that pesticides such as paraquat should be kept at home and specifically locked in a cabinet, not just put in front of you. Myth 2: Oral herbicide suicide is less painful. In fact, “after drinking paraquat, it is too painful”. Oral administration of paraquat can cause burning sensation in the mouth, mucosal erosion and ulceration in the mouth and esophagus, nausea, vomiting, abdominal pain, diarrhea, even vomiting blood, blood in stool, and in serious cases, gastric perforation and pancreatitis; some patients have enlarged liver, jaundice and abnormal liver function, and even liver failure. There may be dizziness and headache, and a few patients experience central nervous system symptoms such as hallucinations, fear, convulsions and coma. Renal injury is the most common, manifested as hematuria, proteinuria, oliguria, elevated blood urea nitrogen, digital radiography, and acute renal failure in severe cases. Lung injury is the most prominent and serious, manifesting as cough, chest tightness, shortness of breath, cyanosis, and dyspnea; non-massive intake patients have a subacute course, with chest tightness and breath-holding occurring mostly in about 1 week, with dyspnea peaking in 2-3 weeks, and patients often die of respiratory failure. Complications such as pneumothorax, mediastinal emphysema, toxic myocarditis and pericardial hemorrhage occur in a few patients. Myth 3 Improper oxygen therapy. There are still medical personnel who do not know enough about the disease or improper oxygen therapy, and routine oxygen administration should be avoided in acute paraquat poisoning. Based on the understanding of the toxicological mechanism of paraquat poisoning, it is recommended that PaO2<40mmHg (5.3kPa) or acute respiratory distress syndrome be considered as an indication for oxygen therapy. Misconception 4 Incorrect choice of hemodialysis treatment method. Since plasma exchange only has the effect of removing toxins with plasma protein binding rate greater than 80% and distribution volume less than 0.2L/Kg, and paraquat is almost free in plasma, it is not recommended to perform plasma exchange. Theoretically, paraquat is a water-soluble and small molecule substance, which is more suitable for hemodialysis. However, since the renal clearance rate of paraquat itself is much higher than the toxic clearance effect of HD, it is suggested that hemodialysis should only be used for patients with paraquat poisoning combined with renal function impairment. Although hemoperfusion lacks evidence-based medical evidence, there is a basic consensus on its role in clearing paraquat, and it is recommended that hemodialysis should be performed as soon as possible after oral poisoning.