There are two major categories of antibodies to syphilis, non-specific antibodies and specific antibodies. The most common tests for non-specific antibodies are RPR and TRUS, called the rapid plasma reactin ring card test, and TRUST, a toluidine red unheated serum test. The higher the RPR, the more severe the disease is likely to be, or to be in the early stages. The VDRL, also known as VDRL, is a microscopic test that is used to observe the results of the test, and is mainly used to test the cerebrospinal fluid of patients with neurosyphilis. The most common methods for the detection of specific antibodies to syphilis are TPHA and TPPA. TPHA is called the syphilis spirochete hemagglutination test, and TPPA is called the syphilis spirochete gel agglutination test. There is also the HTAABS, which is a fluorescent spirochete antibody adsorption test. If it is positive, it usually means that you have been infected with syphilis. Once infected with syphilis, the TPHA indicator will remain in the body for a long time and is generally positive for life. Syphilis infection of the human body, RPR antibodies will generally come out more quickly, the titer is relatively high at first, the titer is when we carry out non-spirochete experimental testing, we directly use the serum to do RPR experiments, the naked eye observed positive results, we judge the 1:1, is the original times. RPR can indicate the status of syphilis infection in the body. If the patient has not been infected for a long time and the titer of RPR is high, it means that the more serious the patient’s condition is. After treatment, the titer decreases more than fourfold, indicating that the treatment is working well. A negative RPR test at the time of review does not mean that there is no more problem, because RPR is a manual test, which has a lot to do with the operation, so there is a possibility of false negatives and false positives, and it is only reliable if the test is repeated at least 3 times negative. It is normal for the results to fluctuate within a factor of 2 between each time. Generally speaking, after regular treatment, the RPR of syphilis patients will turn negative in about 1 to 1.5 years.