The cause of the inflamed lymph node swelling needs to be determined first. The next step is whether anti-infective treatment is needed. Penicillins, such as penicillin, piperacillin or ampicillin, are often used. First- or second-generation cephalosporins can also be used for anti-infective treatment, often cefazolin or cefuroxime, as well as cefoxitin and cefmetazole, which are similar to cephalosporins in the antibacterial spectrum. With effective anti-infective treatment, the swollen lymph nodes can gradually subside. In addition, follow-up blood tests and lymph node ultrasound are required during the treatment process to determine the effectiveness of treatment and the regression of enlarged lymph nodes, and antibiotic adjustments are made according to the efficacy of treatment.