Patient: Description of the condition (onset, main symptoms, hospital visited, etc.): Intercostal pain in the right upper abdomen for 1 year, at first it was not obvious, now it is very painful, usually for 5 to 6 hours, then it gets better on its own. The pain is radiating and sometimes extends to the back, usually once in a month or two. I work at night for a long time, eat irregularly, and work in a sitting position for a long time. Examination in the district people’s hospital: chest X-ray is normal. Ultrasound: Liver is normal. The gallbladder is normal in size: the wall of the gallbladder is 7MM thick, rough, and there is a 21MMX10MM strong echogenic mass in the cavity, followed by acoustic shadow. The common bile duct is normal. Conclusion: cholecystitis, gallstones. The doctor advised me to have surgery, but I’m only 26 years old, so I’m afraid of the sequelae or something. Can you tell me: can I not have surgery? How can I make it painless? And is my ultrasound conclusion correct? Thank you. Patient: I feel like I’m getting a little nervous lately, I like to look up diseases on the internet, I’m still not sure. I’ve read online that stones left in the body for a long time can easily cause gallbladder cancer? And can ultrasound test misdiagnose gallbladder cancer as gallstones? How should I treat it? I’m so young, I can’t have gallbladder cancer, I’m so nervous lately, I’m so busy at work, I’m not ready to go for surgery yet, I’m so annoyed every day. Hepatobiliary Surgery Department of Hepatobiliary Hospital: If the ultrasound description is correct, the diagnosis can be clear, that is, gallbladder stones and cholecystitis. For cholecystitis, if the inflammation does not attack, the pain is usually not strong. Already attacked, you can apply anti-inflammatory, choleretic, antispasmodic drugs, diet less oily and other methods, and apply antibacterial agents if needed. The indications for surgery are clear, and doctors in this specialty will recommend you to consider surgery. Of course, you can choose not to treat it, conservative treatment or surgical treatment. You are welcome. It is recommended to check CEA and CA19-9 to rule out gallbladder tumor. You should still find a good time to have your gallbladder stones opened up. Patient: Thank you Dr. Yi, I feel you are really a good person, few doctors are so patient with their answers. I have now decided to go for laparoscopic surgery, except that I am very busy at work and I don’t know how soon I can be discharged from the hospital. Is there a high risk factor for the surgery? Hepatobiliary Surgery Department, Hepatobiliary Hospital: Mortality rate within 1 month after surgery: about 1 in 1000 for gallbladder removal and about 1 in 100 for surgery such as radical gallbladder tumor treatment.