Osteoporosis is a clinical syndrome caused by a general decrease in bone quantity, an increase in the trabecular space, a decrease in bone matrix and weight, and a decrease in the mechanical strength of bone leading to non-traumatic fractures, or fractures in certain areas that can occur with minor external forces. The etiology and pathogenesis of osteoporosis are not yet fully understood, but the main aspects are as follows: 1. Endocrine disorders It is well known that this disease is mostly seen in the elderly, especially in female patients after menopause. This suggests that: sex hormones have a direct relationship to the metabolism of bone. When the adrenal cortex is hyperactive, it can cause osteoporosis, which is not only the main feature of Cushing’s syndrome, but also the long-term use of adrenal corticosteroids to patients in clinical treatment can also cause this consequence. This suggests that adrenocorticotropic hormones can accelerate the process of osteoporosis. Sex hormones inhibit anterior pituitary hormone, which indirectly inhibits adrenocorticotropic hormone. Therefore, the elderly have less sex hormone secretion, especially women after menopause, are more likely to have osteoporosis. 2, calcium metabolism disorder There is no doubt that calcium deficiency is one of the causes of osteoporosis in adults. The daily calcium intake of normal people is about 10mg/kg body weight, of which a small amount is used by the body and most of it is excreted in urine and stool to maintain the balance of calcium metabolism. If the intake of calcium decreases, or the intestinal absorption dysfunction, or the excretion from urine and stool increases, it will easily cause osteoporosis caused by calcium deficiency. At this time, if coupled with the influence of endocrine disorders, it is more likely to cause osteoporosis. 3, waste factors Under normal circumstances, due to muscle diastolic contraction and various should, pressure and stimulation of bone tissue to maintain a normal balance of calcium metabolism. However, once the limbs or the whole body lose physiological activities and physical labor or exercise, it is easy to cause a series of changes in the bone tissue and lead to decalcification and increased urinary calcium excretion, resulting in osteoporosis. Long-term bed-ridden patients show systemic osteoporosis, while limb plaster splinting or neuropathic disuse shows local osteoporosis. Osteoporosis is mostly seen in the elderly, especially in women over 60 years old. Patients mostly complain of general fatigue, preferring to lie in bed or sit on their backs rather than move around; generalized pain, especially in the lumbar region, may spread from the waist to the hips and lower limbs, and from the back to the ribs and abdomen. In addition to the degeneration of the intervertebral discs, it is also related to the compression fracture caused by the osteoporosis of the vertebral body. The hunchback deformity can be aggravated by the same reason. X-rays show osteoporosis of the spine, with a reduction in bone trabeculae and a fishtail-like depression in the middle of the vertebral body. The degree of pain caused by osteoporosis is much less severe than that caused by lumbar disc herniation, and the X-ray manifestations are very different. The application of sex hormones, high protein and high calcium treatment can reduce the symptoms of back pain.