Depression is characterized by significant and persistent depressed mood as the main clinical feature and is the main type of mood disorder. The etiology of depression is not clear, and current medical science emphasizes that the interaction between genetics and environmental or stress factors, and the point at which this interaction occurs, has an important influence in the development of depression. So what can be done to prevent depression? 1, preventive treatment, under the guidance of the doctor’s help to lift or reduce the patient’s excessive psychological burden and pressure; 2, keep a relaxed mood, have optimism, open-minded spirit; 3, pay attention to maintain adequate sleep, avoid overwork, pay attention to the combination of work and rest, pay attention to the regularity of life; 4, diet should pay attention to take more light rich in nutritious food, pay attention to dietary balance, avoid spicy and stimulating food, eat more Fresh vegetables and fruits. Eat more food to improve immunity to improve the body’s ability to resist disease.