Sertraline hydrochloride tablets are antidepressants of the 5-hydroxytryptamine reuptake inhibitor class and can be used to treat symptoms associated with depression, including depression with anxiety, with or without a history of mania, in addition to sertraline hydrochloride tablets for the treatment of obsessive-compulsive disorder. The drug, which has a white film coating as well as a white core, is a prescription drug and should be taken under professional medical supervision. The side effects of sertraline hydrochloride tablets are relatively small, the safety is good, the interaction with other drugs is relatively small, but generally the efficacy period is long. Patients can continue to take the drug after it has had a significant effect to prevent the reoccurrence of depression and obsessive-compulsive disorder. After taking sertraline hydrochloride tablets, patients may experience certain adverse reactions, including indigestion, nausea, anorexia, insomnia, excessive sweating, palpitations, menstrual irregularities, edema and other symptoms. Patients are advised to communicate with their doctors to determine the next step of treatment once adverse reactions occur. Besides, sertraline hydrochloride tablets are not suitable for all patients, such as those with poor renal function, pregnant women and lactating women should not take them. If patients have allergic reactions after taking sertraline hydrochloride tablets, they should be prohibited to replace them with other drugs, such as fluoxetine and paroxetine, but do not change the drugs without authorization to avoid the risks caused by wrong medication.