We must not follow the footsteps of others. China, including other countries in the process of industrialization, must not follow the same example when formulating its own dietary guidelines and other guidelines; it must not make a joke like following the “high-dose statin” treatment. The first reason is: First, these American guidelines are based on evidence from Europe and the United States and localized evidence-based medicine, not for the Chinese and Oriental people, and the Chinese physique, physical fitness and existing dietary structure are very different from those of the Americans. It is useless for the current situation and trend of cardiovascular diseases in China. Second, cholesterol is the first major risk factor for coronary heart disease and is necessary for the pathological process of atherosclerosis. Even though exogenous cholesterol intake has an inhibitory effect on endogenous cholesterol synthesis in the liver, this negative feedback mechanism is quickly broken with increased exogenous cholesterol intake. The following classic and reproducible animal test results authoritatively illustrate that there is certainly a clear causal relationship between excessive dietary intake of exogenous cholesterol and cardiovascular disease: To accomplish physiological functions, the liver of rabbits is also required to synthesize cholesterol but rabbits of herbivorous animals do not have atherosclerosis. If the diet of herbivorous rabbits is artificially altered and cholesterol and other saturated fats are added to the diet, the pathological process of atherosclerosis will soon begin in rabbits. The following phenomenon of epidemiological results at the population level is more illustrative: in the course of agricultural civilization, when the diet was based on carbohydrates and the nutritional intake was insufficient, the human liver was of course synthesizing endogenous cholesterol, but there was less coronary heart disease; in the course of industrialization, when social products were more abundant, when recipes were improved, and when the intake of cholesterol and other saturated fats was higher, the incidence of coronary heart disease The incidence of coronary heart disease only gradually increased. Before the Great Leap Forward and during the Great Leap Forward period, when cholesterol and other lipid components in people’s diet were very low, it was difficult to find pathological specimens of coronary heart disease for medical teaching, so where did coronary heart disease come from? In those days, the liver of our predecessors was also synthesizing cholesterol, so why was there so little coronary heart disease? After the reform and opening up and the great abundance of social products, the dietary intake of cholesterol and saturated fat increased significantly, and everything was finalized in the big fish and meat and passionate burning alcohol at the wine table and dinner table today, we have just ushered in a vast, increasing, and growing with the times, and a young coronary heart disease team. Third, controlling dietary cholesterol to <200 mg< span=""> per day contributes 3-5% to LCL-C reduction, but cholesterol-rich foods are usually also rich in saturated fat. Keeping saturated fat alone to 7% of total calories can contribute up to 8-10% of LCL-C reduction alone. In an overweight person, a 10-pound weight loss can increase the contribution to LDL-C reduction by another 5-8% – these risk factors are all synergistic, and cholesterol, saturated fat and overweight and obesity are often linked together. Combining all three, the simple “keep your mouth shut and your legs open” can contribute to LDL-C reduction by more than 16-23% – and bear in mind that doubling statins to double the risk of medication adherence and side effects will only result in a 6% reduction! LCL-C benefits! The situation in the US and China is different: the long-standing National Cholesterol Education Program in the US led to the first downward trend in cardiovascular disease incidence in the US in 2008; more than 50% of the US population with high cholesterol is now receiving statin therapy, and about 35% of cholesterol levels are under control. China’s coronary heart disease mortality rate is steadily increasing at a rate of 5% per year, and less than 13% of the population with high cholesterol levels in China is receiving statin therapy, with about 14% of cholesterol levels in control. – The United States has long since completed and long since paid for its industrialization. Most U.S. manufacturing and factories are now “foreignized,” so it is true that most places in the U.S. have blue skies and white clouds most of the time during the day: the U.S. moon is indeed big and full, but the U.S. moon is also cloudy and full! Hopefully: if the US Dietary Guidelines for the Population make the above important changes, do not over-interpret and mislead your patients. In China, “keep your mouth shut and your legs open” and “simple lifestyle 7” are the only proper way to curb cardiovascular disease at its source. One of the important reasons why the US has changed its guidelines is that statins are more commonly used in the US, and statins in the US are sold to patients not by content but mainly by tablets: 20mg of statin and 80mg of statin are both one tablet, with little difference in price, and absolutely most patients, when taking statins, do not The absolute majority of patients, who take statins, do not need to pay for them themselves and buy them online at a bigger discount; statins in China are not cheap for the average citizen and the price difference between taking 20mg and 80mg of statin is huge. The side effects of statins increase with the dose in the therapeutic concentration range; doubling the dose of a statin increases the cholesterol-lowering ability by only 6% – so a low to medium dose of a statin, plus “keep your mouth shut and your legs open” or “simple lifestyle 7” is a good idea. “Simple Lifestyle 7”, is the best cost-benefit ratio and risk-benefit ratio for secondary prevention in most Chinese patients with coronary heart disease. Therefore, we, the Chinese, need to continue to limit the intake of excess cholesterol in our dietary structure. Limiting excess cholesterol intake is definitely not about limiting cholesterol intake to about one egg yolk a day, but about not overdoing it, but about a moderate and balanced amount. We do not need the so-called “Chinese guidelines” that are always translated, copied and pasted from other people’s guidelines. We need our own guidelines based on localized evidence-based medicine. We need to wear Chinese shoes, walk the Chinese road, and live the dream of health – the Chinese dream.