There is no such thing as the best medicine for ichthyosis. Ichthyosis is a hereditary disease, drug treatment can only play a role in controlling the effect of the disease, can not be cured. Ichthyosis can be treated by taking the right amount of vitamin A drugs such as Avicenna under the guidance of a doctor. At the same time, you can apply petroleum jelly, urea cream, etc., in order to achieve moisturizing and reduce the role of scales. Patients with ichthyosis need to pay attention to keep the skin moist and apply more moisturizer to improve the symptoms. Ichthyosis is usually more serious in winter and less serious in summer. Therefore, you should pay attention to skin care and moisturize your skin in winter. For more details, please consult a specialist at a hospital.