1, gout occurs at any age, but the peak incidence is around 40 years of age, more common in men, about 5% of women, and mostly postmenopausal women. Patients often have a family history of genetics, and more with obesity, hyperlipidemia, fatty liver, type 2 diabetes, hypertension, atherosclerosis, coronary heart disease, etc.; 2, the vast majority of patients with gout early without any symptoms, only the performance of hyperuricemia, generally over several years to decades, when hyperuricemia caused by acute arthritis attacks, gout stone, joint lesions, kidney damage, it is called gout; 3, acute Arthritis manifestations: often acute onset, mostly at night, severe pain, joint and surrounding tissue manifestation of redness, swelling, heat and pain, the involvement of the joint bunion and the first metatarsophalangeal joint is the most common, other susceptible joints in order: foot, ankle, heel, knee, wrist, elbow joint. 4. Gout stones: uric acid deposits, which are positively correlated with the concentration and duration of hyperuricemia; mostly located in subcutaneous connective tissue, more common in the auricle, metatarsal toe, interphalangeal, metacarpophalangeal and elbow joints; 5. Patients can develop kidney damage, manifested as proteinuria, chronic renal insufficiency, uremia.