(1) Combination of supporting the positive and eliminating the evil The first and most important principle in treating gallbladder cancer is to identify the deficiency and the real in order to determine the treatment principles of attacking and supplementing. Generally speaking, in the early stage, the evil toxin accumulates in the gallbladder cancer, which accumulates over time, hinders the qi and blood, accumulates into lumps, does not affect the whole body, and the positive qi is not yet deficient, so there are usually no symptoms. If the metastatic lesions are visible, it is a mixture of deficiency and reality, and it is advisable to both attack and supplement, and the treatment is to remove phlegm and soften the firmness, eliminate stasis and disperse the nodules. (2) Combination of disease identification and evidence identification Chinese medicine regards gallbladder cancer as a local manifestation of systemic disease. Due to the differences in congenital endowment, age, disease duration and treatment measures, patients with gallbladder cancer often have individual differences and show different symptoms of the same disease. However, due to the special pathological and biological characteristics of gallbladder cancer, the treatment of gallbladder cancer by TCM should be based on the principles and principles of evidence-based treatment and combined with disease-based treatment to improve the clinical treatment effect. Combining evidence identification with disease identification treatment, that is, identifying disease at the same time of evidence identification, combining traditional theories and experiences of Chinese medicine for many years, and selecting some drugs with proven anti-cancer efficacy for treatment according to the nature, taste, efficacy and clinical application characteristics of drugs. A lot of clinical practice proves that there is a scientific basis that the combination of diagnosis and disease identification can often achieve better results in the treatment of gallbladder cancer. Only with proper combination of disease identification and evidence-based treatment can we obtain better clinical effects. (Physiologically, the liver and gallbladder are mutually related to each other, and the rise and fall of liver and gallbladder qi is closely related to the rise and fall of spleen and stomach functions, therefore, once the disease develops, liver, gallbladder, spleen and stomach will bear the brunt. In clinical diagnosis, attention should be paid to the identification of internal organs, deficiency, qi and blood, cold and heat, dredging the liver and gallbladder, regulating qi and lowering, combined with strengthening the spleen and benefiting qi as the basic treatment method, which can significantly improve the efficacy. (4) Pay attention to the clinical application of Chinese medicine “survival with tumor” In the treatment of gallbladder cancer, the overall situation of the whole body is fully weighed against the local tumor, and through the balance of tumor suppression and regulation of the body (the combination of overall treatment and local treatment), we strive to make the tumor in a dormant state, so as to create conditions for survival with tumor and improve the quality of survival. The clinical practice proves that there are many cases of “long-term survival with tumor” through TCM biological health care comprehensive treatment.