If a thyroid nodule is removed by minimally invasive surgery, the indications are generally benign thyroid nodules, such as adenomas, cysts or smaller nodules, preferably within 5 cm in diameter suitable for minimally invasive removal. The surgical operation requires the selection of a pathway first. There are many pathways according to the patient’s own situation and the most appropriate one can be chosen. The thyroid gland can be removed by cutting through the white line of the neck, separating the connective tissue between the muscle and the thyroid gland, opening the peritoneum of the thyroid gland shell and then moving away from the recurrent laryngeal nerve, cutting off the blood vessels with an ultrasonic knife and freeing the thyroid gland. After surgery, the specimen can be sent to a specimen bag or a 1 cm incision can be made to remove the nodule for quick pathological examination, rinse the surgical field for adequate hemostasis, suture the muscles of the anterior cervical region and the white line of the neck to place a drainage tube to drain the subcutaneous gas and close the incision.