Pathological cerebral atrophy varies from early to severe depending on the cause and can range from months to decades and cannot be generalized. Cerebral atrophy is a phenomenon in which organic lesions of brain tissue occur due to various causes, producing atrophy. The pathology is characterized by a reduction in the volume of brain tissue, a decrease in the number of cells, and an enlargement of the ventricles and subarachnoid space. It is more common in men than in women and can be divided into diffuse brain atrophy and limited brain atrophy. Cerebral atrophy is not an individual disease, but a neuroimaging manifestation of many diseases, such as cerebrovascular disease, encephalitis, traumatic brain injury, long-term heavy alcohol consumption, long-term exposure to toxic substances, etc. The main manifestations are cognitive impairment and personality changes. Elderly people with increasing age and severe cerebral arteriosclerosis can also develop brain atrophy without obvious clinical symptoms, which is often detected by the reduction of brain tissue volume and enlarged ventricles during CT or MRI examinations. In addition, once the diagnosis of cerebral atrophy is confirmed, in addition to strictly following medical advice on medication and regular review, a good daily lifestyle, such as regular rest and rest, proper exercise, a diet with less oil and sugar, and abstinence from smoking and alcohol, should be adopted.