Mild microcephaly may be caused by hereditary factors, degenerative diseases, or natural aging of the person, so treatment is tailored to the patient’s cause. Although there is no particularly effective approach to microcephaly, the main focus is to intervene on controllable causative factors to slow down the patient’s disease progression. Medication is mainly a treatment to improve the patient’s ataxia. If the patient has ataxia, the patient can be given drugs such as buspirone and tandospirone. It improves the symptoms of ataxia and also has anxiolytic and antidepressant effects. Preventive treatment for the causes of cerebellar atrophy, for example, patients with cerebellar atrophy because of insufficient blood supply to the brain, resulting in the patient’s cerebral vessels in a state of ischemia and hypoxia and causing brain tissue atrophy, should be given to patients to activate blood stasis, improve brain metabolism drugs to slow down the progress of the disease. For example, the patient should be given oral medications such as Ginkgo biloba, blood Cetron tablets, Olacitant, and cytarabine sodium tablets.