The establishment of a treatment plan for nephritis is largely based on the type of pathological damage to the kidney. The treatment will be different for different types of nephritis. In general, the treatment of nephritis includes several aspects: 1. control the systemic symptoms caused by nephritis; 2. reduce and improve the inflammatory damage of kidney tissue; 3. prevent or correct comorbidities or complications. The core of kidney disease treatment is to prevent the deterioration of kidney function rather than simply improve proteinuria or hematuria. 1.Control the systemic symptoms caused by nephritis When nephritis attacks, it often shows swelling, weakness, hypertension, oliguria, carnituria, etc. Some patients also have symptoms of the digestive tract, such as nausea, vomiting, anorexia, etc. The reason for these symptoms is mainly related to the decrease of protein concentration in the blood caused by a large loss of protein in the body through urine. For mild edema, it can be controlled by low salt diet and water restriction or appropriate diuresis; while for severe edema, in addition to the above measures, human albumin, plasma and related substitutes can be imported to increase plasma osmolality to enhance diuretic response. 2.Control the inflammatory reaction in the kidney Immunosuppressants can inhibit or reduce the inflammatory reaction in the kidney tissue, improve proteinuria and hematuria, and relieve the kidney lesions transiently. Commonly used immunosuppressants are glucocorticoids (prednisone), some drugs that inhibit the anabolism of inflammatory cells (cyclophosphamide, azathioprine, mycophenolate and some monoclonal antibodies, etc.); some traditional Chinese medicines (such as Leigengteng) also have a strong immunosuppressive effect. It should be noted that these drugs have strong side effects or side reactions, dosage and use time should be strictly controlled, do not use blindly without purpose. 3.Reduce the workload of the kidney When the kidney is diseased, the working pressure of the glomerulus (glomerular perfusion pressure) rises significantly. Effectively reducing glomerular work pressure can improve proteinuria and slow down the progress of the disease. Commonly used drugs include renin-angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists. These drugs need to be used early and maintained for a long time to achieve maximum efficacy. Both converting enzyme inhibitors and angiotensin II receptor antagonists can also effectively lower systemic blood pressure, so they are especially suitable for patients with massive proteinuria and hypertension. For patients with normal blood pressure and patients with severe renal insufficiency, blood pressure and renal function need to be monitored. 4, prevention of comorbidities nephritis patients are very easy to combine infection, thrombosis, malignant hypertension and other comorbidities, in the process of kidney disease treatment need to pay attention to control blood pressure, correct hyperlipidemia, hyperviscosity, improve their own physical fitness, finally it is worth emphasizing that drug therapy is only a small part of the treatment process of kidney disease, chronic kidney disease treatment is the most important part of the search for the cause and aggravating factors (bad The most important part of chronic kidney disease treatment is to find the causes and aggravating factors (bad living habits and dietary habits), enhance physical fitness, and avoid some artificial factors to induce or strengthen the disease (such as abuse of antibiotics, intravenous infusion).