Dichlorvos poisoning 15 days did not wake up, belongs to the moderately severe poisoning, it is recommended to give blood perfusion treatment, while continuing to apply detoxification drugs, to promote the excretion of poison, to protect the function of vital organs. Dichlorvos poisoning, first of all, you should take first aid measures, stop contact with the poison, out of the poisonous environment. Patients who have been poisoned orally should be immediately emetic and gastric lavage. Patients with moderate to severe poisoning may require repeated gastric lavage and the use of antidote drugs such as antiphosphidine and atropine as soon as possible. If the patient remains unconscious for 15 days after the above treatment measures, blood perfusion is needed to detoxify the patient. The patient’s coma after dichlorvos poisoning is a neurological symptom, and the root cause is that dichlorvos has not been completely removed, so the primary goal of treatment is to remove dichlorvos from the blood, and blood perfusion is a good way to remove large molecules of toxins from the blood. In addition, for dichlorvos poisoning 15 days did not wake up the patient, we should pay attention to monitor their cardiopulmonary function, open the airway, prevent respiratory muscle paralysis, prevention and treatment of shock and cerebral edema, maintain the water electrolyte balance, and prevent infection. Dichlorvos poisoning 15 days did not wake up, please actively cooperate with the doctor’s treatment, and do a good job of patient’s life care, keep clothing and bed units clean, turn over regularly to prevent pressure sores.