The treatment methods of motor neuron disease are as follows: 1, medication: anti-excitatory amino acid toxicity drugs can be used to slow down the development of early disease, through myorelaxants, antioxidants, etc. to reduce the patient’s joint contracture, joint stiffness, drooling and other symptoms; 2, oxygen therapy: for patients with respiratory weakness, home simple ventilator oxygen therapy can be used to reduce the patient’s symptoms of respiratory distress or respiratory failure; 3, surgical treatment If the patient has swallowing dysfunction, a gastric tube can be placed in the short term, and gastrostomy can be performed in the long term; 4.Psychotherapy: psychological assessment and psychological guidance can be used to help the patient understand the disease and face the disease. The specific medication should be combined with the clinical situation and guided by the doctor’s interview.