The main symptoms of depression are depressed mood, unhappy, feeling sullen, no sense of joy, sad face, long sighs, heavy cases can be painful, pessimistic and desperate, with a sense of life as a year, life is worse than death. Typical cases of depressed mood are more severe in the morning and less severe in the evening. Next is slow thinking. Thinking and associating slowly, slow reaction, feel as if the brain is a rusty machine, the brain like a layer of paste coated. Becoming indecisive, indecisive, even for some small daily matters also difficult to make decisions. The evaluation of oneself is lowered and one considers oneself useless and worthless, or in severe cases, one blames oneself and feels useless, helpless and hopeless. Feeling isolated, unable to seek help from others, and others are unable to help themselves; pessimistic and disappointed about the future, despairing of the future, feeling that the future is like a gray sky with no hope. The last manifestation is a decrease in volitional activity. Slow behavior, passive life, lazy, do not want to do anything, do not want to contact with people around, often sit alone, or lie in bed all day, do not want to go to work, do not want to go out, do not want to participate in the activities and hobbies they usually like, often closed door and live alone, alienated friends and relatives, avoid social. In severe cases, even food, drink and personal hygiene are disregarded, with unkempt hair and unkempt face. In severe cases, patients often have self-injurious, suicidal and injurious behaviors, which are the most dangerous symptoms of depression and should be vigilant. In addition to the above manifestations, patients with depression will have cognitive impairment and somatic symptoms. The manifestations include sleep disturbance, fatigue, loss of appetite, weight loss, constipation, pain in any part of the body, loss of libido, impotence, amenorrhea, etc. Sleep disorders mainly manifest as early awakening, usually 2 to 3 hours earlier than usual, and the inability to fall back to sleep after waking up, which is characteristic for the diagnosis of depression. Some of them show difficulty in falling asleep and not sleeping deeply; a few patients show excessive sleep. Memory loss, attention deficit, increased alertness, learning difficulties, poor verbal fluency, and reduced spatial perception, eye-hand coordination, and mental dexterity occur. These symptoms led the patient to believe that it was a somatic disease, and first went to a general hospital for consultation, where extensive physical examination did not reveal organic disease. Repeated examinations and medical visits and minimal results often aggravate the pessimism of patients, who believe that there is no cure. Depression can also manifest itself differently at different ages. Recognizing the following manifestations can help us detect depression early. In children and adolescents, if children are found to be reluctant to go to school, their academic performance decreases, they develop headaches, stomach pains and tummy aches, poor relationships with partners and adults, aggressive behavior, suicidal thoughts and behaviors; middle-aged people appear irritable and irritable, moody, pessimistic and desperate, feeling that life is meaningless, helpless and hopeless about life. The middle-aged people appear irritable and irritable, feel pessimistic and desperate, feel that life is meaningless, feel helpless and desperate about life. They belittle themselves, feel worthless, blame themselves, feel sorry for their family and friends, even feel that they have serious sins, or have serious untreatable certain diseases, or are penniless, feel that the world around them is not real, even feel that they and the world no longer exist; the elderly people appear somatic discomfort symptoms such as headache, dizziness, palpitation, chest tightness, general pain and discomfort, constipation, frequent urination, etc., for a long time in various If you have been treated in various general hospitals for a long time without any obvious abnormality in all tests and the treatment effect is not satisfactory, you should think about whether the above symptoms exist due to psychological reasons. In these cases, you should be alert to the possibility of depression and go to a specialized hospital for timely treatment.