Patients with depression can have very painful emotional experiences, most notably because these patients have depressed moods, lack of interest, and a lack of cheerfulness. Things that used to interest them are not currently interesting, and things that used to cheer them up are currently not making them happy. These problems will make themselves especially painful, and at the same time they will become inferior, self-blaming and self-criminal, feeling that they have dragged their families down, and even pessimistic and disappointed about the future, lacking a sense of hope, which makes it difficult to be happy at this time. At the same time, attention and memory are reduced, cognitive function is impaired, thinking is slowed, and the efficiency of study or work is greatly impaired, which can cause great damage to one’s social function. After the impairment of daily living ability and social function, patients will have a lot of painful emotional experiences. There are also many signs of physical discomfort, such as headache, dizziness, nausea, vomiting, loss of appetite, poor sleep, etc. These symptoms of physical discomfort can also add to the painful experience.