Depression performance varies in severity, with a variety of symptom variations, common treatment methods are: first, medication, different drugs should be selected according to different symptoms, depressed patients with anxiety and agitation should choose antidepressants with sedative effects, such as paroxetine, mirtazapine, trazodone. Depressed patients with strong obsessive-compulsive and panic disorder are recommended to apply drugs such as fluvoxamine and sertraline. Patients with depression accompanied by hallucinations, delusions and other schizoid symptoms are recommended to combine the application of antipsychotic drugs, such as olanzapine, risperidone, quetiapine, etc. Second, electroconvulsive therapy, electroconvulsive therapy is mainly aimed at patients with refractory depression who are mute, have strong suicidal thoughts and refuse to eat. Third, psychotherapy, psychotherapy is more effective for patients with mild depression, mainly through cognitive-behavioral therapy to improve the patient’s cognitive irrationality and rebuild the cognitive system.