Liver is the root of fatigue. Long-term strain, strain hurts liver qi, liver qi deficiency, eyes sore and easily fatigued; qi does not move up, fluid can not spread head and face, then dry mouth and face; qi does not carry blood up, then brain ischemia, dizziness of the head and eyes, blurred vision, unclear thinking, yellow face; liver qi deficiency, liver meridian congestion, easily injured by summer dampness, easy to heat stroke. Diagnosis: Liver Qi deficiency and Liver Blood deficiency are both seen in numbness of the limbs, lack of claw and nail, diminished vision, and menstrual diffusion. As the sutra says, “Qi is the master of warmth, and blood is the master of moistening”. Qi deficiency, tendon relaxation, stretching weakness is the main, each with cold signs, such as cold limbs, limbs are not warm. In the case of blood deficiency, the numbness of the limbs and the throbbing of the muscles are the most common, and often accompanied by signs of deficiency heat, such as hot flashes and night sweats, and irritability of the five hearts. Chinese medicine believes that “Qi is the root of man”. Huang Yuanqing emphasizes that “nine out of ten people have insufficient qi”. Qi is the basic material manifestation of human life activities. Physiologically, the normal function of the five organs depends on the qi of the five organs, pathologically, the dysfunction of the internal organs can also cause abnormal qi of the organs. Liver qi deficiency is one of the abnormalities of liver qi and is a major pathological mechanism of liver dysfunction. The theory of internal organs identification is imperfect if liver qi deficiency is denied or ignored. All five organs have Qi deficiency, but not the liver, which is a limitation in understanding and thinking. The neglect of liver qi deficiency directly leads to the gap in clinical evidence of “liver qi deficiency”. “This is a limitation of understanding and thinking. The root cause of chronic hepatitis that is difficult to heal is Zheng deficiency, mainly Liver Qi deficiency. The deficiency is not able to resist the evil out, and the long existence of evil further aggravates the deficiency. Liver Qi deficiency is a pathological manifestation of the disease after long-term development and evolution. In conclusion, paying attention to liver qi deficiency can not only enrich theoretically the understanding of liver diseases and difficult diseases, but also expand the clinical thinking.