Ibuprofen is not effective for patients with headaches. Ibuprofen treats neuropathic headaches. If the patient’s headache is due to intracranial occupational lesions, or hypertension and intracranial infections that cause headache symptoms, ibuprofen is ineffective. It is recommended that the patient’s headache should still be identified as the cause, and an MRI scan of the head can be done at the hospital to determine the diagnosis. If the patient has a neuropathic headache, the patient can be given two courses of oral treatment with Zhengtian Pill. It is necessary to find out whether the patient often eats spicy and irritating food in daily life or often eats seafood and crabs and other foods, and the symptoms of headache are not easily relieved.