A person with a history of hepatitis B or HBsAg positivity for more than 6 months who is still positive for HBsAg and/or HBV DNA can be diagnosed with chronic hepatitis B virus infection. Chronic hepatitis B virus infection includes: a. Chronic hepatitis B refers to those with positive surface antigen, repeatedly increased transaminases and significant inflammatory activity of liver tissue. Yang Yongfeng, Department of Hepatology, Nanjing Second Hospital II, hepatitis B cirrhosis Hepatitis B cirrhosis is the result of the development of chronic hepatitis B. It can be further classified according to the liver function compensation: 1, compensated cirrhosis There may be mild weakness, loss of appetite or abdominal distension symptoms, ALT and AST may be abnormal, but there is no obvious liver function loss performance. There may be signs of portal hypertension, such as hypersplenism and mild esophagogastric varices, but there is no bleeding from ruptured esophagogastric varices, no ascites and hepatic encephalopathy, etc. Patients with decompensated cirrhosis often have serious complications such as rupture and bleeding of esophagogastric fundic varices, hepatic encephalopathy and ascites. Most of them have obvious loss of liver function, such as serum albumin <35g/L, bilirubin >35μmol/L, ALT and AST are increased to different degrees, and prothrombin activity (PTA).