There are some misconceptions about whether mental illness can be cured. The general understanding of disease cure is an absolute cure, that is, after a certain course of treatment, no longer suffering from the same disease for the rest of one’s life. Such a cure is actually rare, including not many surgical diseases that can be treated surgically, acute appendicitis being one of them, and after the surgical cure because there is no more appendix the disease will no longer appear. Many other medical and surgical diseases are not guaranteed for life. The same goes for psychological disorders, where the likelihood of a lifetime free from the disease is very small and there is little research data on this. The medical term “cure” usually refers to clinical recovery, which means complete remission of symptoms for a certain period of time without recurrence, sometimes with the addition of the degree of functional recovery to be considered cured. The term cure for mental illness also refers to clinical cure: complete remission of symptoms and return to normal self-awareness. Therefore, in terms of this criterion, there are many psychological disorders that can achieve clinical recovery, and the percentage of patients with each psychological disorder that can meet the criteria for recovery is quite large. The gap between clinical cure and the patient’s desired cure is a problem that cannot be avoided, and the doctor must do his best to bring the patient closer and closer to his own goal. However, after clinical recovery of a psychological disorder, the chance of relapse is indeed quite high if maintenance treatment is not continued for a long enough period of time. Therefore, how to maintain treatment is a very important issue. Maintenance therapy should be based on the principles of adequate dosage of medication, minimal side effects, convenience of taking medication, economic maintenance, and sufficient duration. The maintenance dose of psychiatric drugs has tended to be the therapeutic dose, because more studies have found that the chances of relapse in patients on a maintenance dose are less than those on a half or one-third of the maintenance dose as guided by previous textbooks; the maintenance dose reaches the therapeutic dose, which inevitably leads to a high incidence of side effects, inconvenience in taking medication, and high drug costs for a long time, resulting in a decrease in treatment adherence. Patients therefore stop maintenance therapy on their own. Therefore, the physician has to choose between these contradictions and negotiate with the patient to choose the maintenance regimen that best suits the patient’s needs. Therefore, as mentioned above, it is important to trust the physician and choose the best maintenance regimen. How long is the maintenance period considered long enough? In fact, although there are textbooks guiding the duration of maintenance therapy, the duration of maintenance should be different because the patient’s condition is different, and individualized consideration of maintenance duration I think is more important and can be long rather than short. From my personal follow-up cases, I found that as long as the amount of maintenance treatment solves the problems of side effects, convenience of taking medication, and the cost of maintenance treatment, it has been maintained for 5 to 10 years, and do not arbitrarily change the treatment plan, if you can achieve while taking medication, study or work, without affecting their social function, even if successful. The last point is to treat the contradiction between medication maintenance and cure correctly. People generally think that if you are cured, you don’t need to take medication, and if you are taking medication, it proves that you are not cured. We do not need to be overly concerned about this issue, but can be more realistic or utilitarian. As long as one’s social function is the same as before the disease or close to it, one can afford it financially, and there is no physical discomfort, there is no need to dwell on the question of whether one should stop taking the medication, as taking the medication allows one to maintain a normal life, and why try to stop the risk of relapse. In fact, there are too many clinical cases that like to try to stop the medication. Here again, we call for adherence to standardized maintenance treatment and readiness to fight a protracted battle to prevent relapse of the disease.