Surgery + choledochoscopic stone extraction is the best option for the treatment of intrahepatic bile duct stones! For patients with combined intrahepatic bile duct stones, in principle, it is not advisable to take EST (duodenal papillotomy) to remove stones, so as not to damage the function of the sphincter and destroy the airtightness of the bile ducts leading to reflux, but rather to take a combination of surgery and choledochoscopy principle, to avoid blind ERCP / EST to remove the stones, of course, in the case of intrahepatic choledochal calculi accompanied by acute obstructive cholangitis, the adoption of ENBD can be made possible! , which fights for the chance of surgical treatment. In addition, ERBD (endoscopic biliary drainage) is also feasible for patients of advanced age who are difficult to tolerate surgery, to relieve the obstruction of the common bile duct and alleviate the symptoms.