HPV16 positive does not necessarily lead to cervical cancer. The probability of getting cervical cancer with HPV16 infection is relatively high. Persistent high-risk HPV infection is the main risk factor for cervical cancer, and more than 90% of patients are accompanied by high-risk HPV infection. In addition to persistent HPV infection, cervical cancer may also be related to multiple sexual partners, early sexual life, multiple pregnancies, multiple births, and smoking. Cervical cancer is a relatively common gynecological malignancy in women and can be cured if detected early. Regular cervical screening is very important, and women can also prevent cervical cancer through HPV vaccination.