There are many different HPV subtypes, including high-risk and low-risk, and it is mainly the persistent high-risk HPV infection that can cause cervical cancer. Low-risk HPV infection rarely causes cervical cancer. Among the high-risk subtypes, the most common high-risk types are 16 and 18. HPV type 18 is positive and colposcopy is recommended. If the colposcopy is negative, cervical lesions are ruled out. If the colposcopy is positive, a biopsy will be taken to confirm the diagnosis. The probability of cervical lesions in patients with positive HPV 18 can be more than 10%. Therefore, a positive HPV type 18 must be treated with caution. However, don’t panic and don’t be afraid. Being infected with HPV type 18 does not mean that you have cervical cancer. Colposcopy should be done and pathology is needed to confirm the diagnosis.