HPV18 positive indicates infection with high-risk HPV18, a type of human papillomavirus, which belongs to the high-risk type. HPV18 infection is closely related to cervical lesions, and may even have cervical cancer. The patient has been infected for a relatively short period of time and has not caused cervical lesions, which is generally not serious. Under normal circumstances, persistent infection with HPV18 virus increases the chance of developing cervical cancer. HPV18 positive, if the body has high immunity and the local immune environment of the cervix is normal, cervical infection with HPV18 virus usually turns negative naturally within 2 years in more than 90% of people and does not cause cervical lesions. If there is no cervical lesion, regular TCT and HPV examination are needed for early detection, early diagnosis and early treatment; interferon pessary and photodynamic therapy can also be applied to promote the conversion, and the chance of cervical lesion will be greatly reduced after the conversion. If HPV18 is positive, the viral infection lasts for 2 years or more, with high viral load and poor cervical local environment, it may continue to develop in a serious direction and progress to cervical intraepithelial neoplasia, precancerous lesions or even cervical cancer, which is generally more serious and should be taken seriously. In daily life, you should also pay attention to eating less spicy, greasy and stimulating food, not to have intercourse during menstruation, and pay attention to menstrual hygiene.