Ankylosing spondylitis belongs to the category of “paralysis” in Chinese medicine, which is characterized by pain in the lumbar spine, swelling and pain in the joints, restriction in the movement of both hips, and even stiffness of the lumbar spine and deformation of the spine. Traditionally, it is believed that this disease is due to deficiency of endowment, deficiency of liver and kidney, wind, cold, dampness, heat and other evil spirits taking advantage of the deficiency, involving the kidney meridian, the bladder meridian and the Governor’s Vessel, thus classifying this disease as “kidney paralysis”, “bone paralysis”, “tortoise back” and “Governor’s Vessel disease”. This disease is classified as “kidney paralysis”, “bone paralysis”, “tortoise back”, “disease of the Governor’s Vessel”, etc. Han Shuhua, Department of Rheumatology and Immunology, Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine Ankylosing spondylitis is the key disease and advantage of our department. Under the leadership of Prof. Ding-Ya Fang, our department has summarized the experience of our predecessors, absorbed the research results of modern medicine, and interrefered with the pathology of Chinese and Western medicine, and after years of clinical practice, we are the first in the Chinese medical field to propose the academic view that this disease belongs to the category of “tendon paralysis” in Chinese medicine. In terms of treatment, we have proposed the academic theory of “relieving spasm and relaxing the governor” as the main treatment for ankylosing spondylitis, and after repeated clinical verification, we have formed a more complete treatment system. According to the different conditions of the patients, our department adopts the Chinese medicine soup “relieving the spasm and soothing the governor” as the main treatment, together with the Chinese medicine injection infusion, acupuncture, physical therapy and other Chinese medicine comprehensive therapy to treat this disease, which has the advantages of fast onset of action, less side effects, lasting efficacy, and not easy to relapse, and has achieved remarkable clinical efficacy, which has been praised by the majority of patients.