Scleroderma in fifteen year olds is usually treated with medications to reduce inflammation levels, maintain immune balance, halt disease progression and combat complications. Scleroderma is an autoimmune disease that can involve multiple organs and systems, and there is no effective cure. Scleroderma disease is categorized into the swelling stage, early sclerosis, late sclerosis and atrophic stage. Patients in the swelling and early sclerosis stages can be treated with medium to high doses of hormones, cyclophosphamide, gammaglobulin and plasma exchange to control the acute phase inflammatory response. For the treatment of late sclerosis and atrophic stage is mainly to control the disease progression and prevention of complications, small doses of hormones, methotrexate, morphimecophenol ester, tacrolimus and other drugs can be used to maintain the immune balance, and patients with Raynaud’s phenomenon and fingertip ulcers can be treated with prostaglandins, nifedipine, sildenafil, simvastatin and other treatments. In addition, for the occurrence of scleroderma renal crisis patients also need to use captopril, enalapril and other angiotensin-converting enzyme inhibitors to control hypertension, for the complication of esophageal reflux disease, esophageal stenosis, ulcers and other diseases of the patients need to timely application of omeprazole, cimetidine and other acid-suppressing drugs to inhibit the secretion of gastric acid and so on. All of the above drugs need to be used under the guidance of a physician, it is recommended that patients diagnosed with scleroderma go to the rheumatology and immunology department of a regular hospital, and follow the doctor’s instructions for treatment.