The term “fire-depression” was first mentioned in Suwen – Six Elements of the Great Treatise on the Righteousness. It is a common pathological basis for a series of illnesses and covers a wide range of conditions. The term “fire-heat” is a treatment method for “fire-heat”, which means “suppressing” and “sending”. The “fire-heat” depression in the internal, when the hair and over the, the benefit and guide. 1, the cause of fire depression fire depression, the cause of the four: one for the external evil deterrence, gas does not flow; two for the emotions hurt, qi depression; three for the deficiency and discouragement of vital energy, the inability to get in and out of lift; four for the diet and fatigue, damage to the spleen and stomach, lifting and reversing, Yang depression does not reach. Anyone who can affect the flow of Qi can cause Yang to turn into fire, thus becoming fire-depression. 2, the treatment of fire depression On the treatment of fire depression, the key is to promote the flow of qi and clear the heat of depression. There are many prescriptions for the treatment of fire-heat, but he is good at lifting and lowering San, and regards it as a general formula for fire-heat, and adds, reduces, and tailors it to achieve good results. It is composed of four herbs: white silkworm (fried in wine), whole cicada shed, wide ginger yellow (peeled), and Sichuan rhubarb (used raw). The formula is based on Silkworm as the ruler, Cicadelle as the minister, Ginger as the adjuvant, and Rhubarb as the messenger. The silkworm is light, floating and ascending, it can clear heat and depression, dispersing the phlegm of rebellion and stagnation, “to clear and ascend Yang”; the cicada is a clearing and deficiency product, good at clearing heat and detoxification, “to clear deficiency and disperse fire”; ginger Huang is cold and non-toxic, “to dispel evil and cut down evil, move Qi It is a non-toxic, cold medicine, which is good at clearing heat and detoxifying, “to clear deficiency and disperse fire”; Jiang Huang is cold and non-toxic, “expelling evil and dispersing stasis”; Da Huang is cold and non-toxic, which is good at suppressing hyperactive Yang and directing heat, draining heat and detoxifying. Although the medicine has four flavors, it is well-matched, using cold and warm, and lifting and lowering together. The name of the formula is “Lifting and Lowering San”, which means “to take the silkworm and cicada molasses to ascend the clear yang in yang, and turmeric and rhubarb to descend the turbid yin in yin, one ascending and one descending, to harmonize inside and outside”. It is a good formula for treating fire and depression, as it can raise the clear and lower the turbid, pass through the lining and reach the surface, move the Qi and invigorate the Blood, and penetrate the heat.