Mothers who have syphilis can transmit it to their newborns. After the mother’s fourth month of pregnancy, syphilis spirochetes can be transmitted from the mother to the fetus through the placenta and umbilical vein. Syphilis can also be transmitted from the mother to the newborn through the placenta and umbilical vein. During delivery, the newborn can also become infected through head and shoulder abrasions during the birth canal, resulting in syphilis transmission. Syphilis transmitted from mother to newborn is also called congenital syphilis. Newborns with congenital syphilis are often premature, with poor development and nutrition, emaciation, loose skin, elderly-like appearance, weak or hoarse cry, restlessness, in addition to skin and mucous membrane damage, mostly after three weeks of life, but also after birth, with various types of rashes on the palms and soles of the feet, often forming around the mouth and anus chalazion, and also tend to develop syphilitic rhinitis, mostly occurring 1-2 months after birth, or cause bone syphilis, which is also more common. There are other damages, including generalized lymph node enlargement, liver and spleen enlargement, anemia, and stunted growth.