Syphilis rash is a clinical manifestation of syphilis stage II (or sometimes stage III). When syphilis stage I is not treated regularly, syphilis spirochetes enter the patient’s bloodstream and spread through the bloodstream to all organs of the body, including the skin. When syphilis spirochetes enter the skin, they multiply locally. The skin damage is mainly distributed in the trunk, the extremities and shoulders can also appear, and there are many different manifestations, generally symmetrical distribution, extensive, no itching, identify the following: 1, spotted syphilis rash: also called rose rash, is the initial appearance of syphilis rash, red, brown or pigmented rose rash, mostly in the trunk began to occur, and then developed to the extremities, palms and soles of the feet, etc.. The erythema is round, sometimes with collar-like flaking around the edges, and is basically symmetrical in distribution. The rash of syphilis is like a “magician” that can imitate a variety of skin diseases, so it is usually difficult to diagnose directly through the characteristics of the rash, but if there is such a rash on the palms of the hands and soles of the feet, it is more suggestive; 2, papular syphilis rash: with the development of the disease, some spots can thicken into a papular rash, which occurs on the trunk, buttocks, calves, palms, soles and face. The rash may appear on the trunk, buttocks, lower legs, palms, soles of the feet and face. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. The damage is smooth, thick, flat, with a mildly broken surface, or covered with gray film; 4, mucosal plaque: about 30% of patients with second-stage syphilis have oral mucosal damage, also called mucosal plaque. The damage is covered with gray film and contains a large number of syphilis spirochetes. Stage II syphilis usually occurs 6 weeks to 6 months after infection. Syphilis rash does not cause much pain to the patient and is therefore often overlooked by patients. In clinical practice, if you see a widely distributed, symmetrical rash with mild self-conscious symptoms, you should consider it to be a stage II syphilis rash.