Syphilis is a chronic, systemic sexually transmitted disease caused by the pale (syphilis) spirochete. It is mainly transmitted through the sexual route and can be clinically manifested as stage I syphilis, stage II syphilis, stage III syphilis, latent syphilis and congenital syphilis (fetal syphilis). It is a disease listed as category B in the Prevention and Control of Infectious Diseases Law of the People’s Republic of China. How is syphilis detected? The common methods of examination for syphilis are dark field microscopy, syphilis serology and histopathological syphilis staging examination. If you find symptoms of syphilis, you should immediately go to a regular hospital for relevant examinations, and now we will introduce you the examination methods of syphilis. 1, syphilis serological examination: 2, non-syphilis spirochete antigen test: detection of anti-cardiolipin antigen antibodies (reactin) in the serum, including venereal disease research laboratory (VDRL) test, non-heated serum reactin (USR) test, rapid plasma reactin (RPR) test, such tests are easy to operate, can be used for screening, but also quantitative test for efficacy evaluation. 3, syphilis spirochete antigen test: including syphilis spirochete hemagglutination test (TPHA), syphilis spirochete particle agglutination test (TPPA) and fluorescent spirochete antibody absorption test (FTA-ABS), etc., sensitivity and specificity are high, can be used to confirm.