1, psychological: relax, keep a happy mood, establish confidence to overcome the disease. 2, diet: to light appropriate, a small number of meals, varied patterns, to high calorie, high protein and high vitamin easy to digest non-slag diet, less spicy and stimulating food. 3, oral ulcers: oral ulcers painful, open mouth and eating difficulties, available gentamicin 320,000 U plus saline 25ml dip cotton ball clean mouth, twice a day, and then ice borax local rub, and then give the same concentration of wet gauze outside the mouth and lips, twice a day. You can also use 1:5000 furacilin gargle. If the pain is intolerable, gargle with 1% nufcaine solution. 4, external genital and perianal ulcers: to keep the local clean and dry, with 0, 2 ‰ potassium permanganate solution after the sitz bath, with 0.1 Levanon clean foreskin, glans or perianal ulcers secretions, coated with erythromycin ointment or gentamycin ointment, to avoid adhesion and friction between the trauma and underwear, to keep the perineum clean. Married women should avoid sexual intercourse when vulvar and vaginal wall ulcers are aggravated. 5, ophthalmia: patients with blurred vision, vision loss, conjunctival congestion, eye pain, use atropine eye drops to dilate the pupil, 0.5% cortisone eye drops to prevent post-inflammatory adhesion of the pigment membrane, keep hands clean when dropping eye drops, the drops should not touch the eyelashes to prevent infection, and pay attention to prevent damage to the cornea. Apply erythromycin eye ointment to the eyelids before going to bed; if you have photophobia, tearing, foreign body sensation and flying mosquitoes, you should watch less TV, books, take rest and wear a sun hat or sunglasses. Do not wear contact lenses to prevent corneal ulcers. For corneal ulcers, apply localized gentamycin ointment and cover with sterile gauze to promote ulcer healing. 6, skin damage: skin damage including pustules, folliculitis, boils, erythema multiforme, blisters, cellulitis-like lesions, furunculosis-like moss, erythema nodosum and skin prick reactions. It is necessary to bathe regularly, change clothes regularly, keep the skin clean, and apply hot compresses or topical medications to the local skin to promote the dissipation and absorption of inflammation, and avoid squeezing. In case of rupture, treat the wound according to surgical asepsis, drain locally with oil gauze, and change the medication once a day. Avoid simultaneous multi-point puncture to reduce the needle reaction. 7.Patients with joint damage: Patients with combined arthralgia or arthritis should rest in bed, elevate the painful limb and adopt a comfortable position to reduce pain, and increase activities appropriately after the condition is stable and pain is reduced. 8.Patients with central nervous system involvement: Pay attention to effective treatment as prescribed by the doctor to prevent fall damage. Keep the limb in a functional position and massage regularly to prevent contracture deformity; when the lesion involves the crestal medulla, urinary incontinence or urinary retention may occur, and the perineum should be kept clean and dry when incontinent. 9, other: regular life, moderate work and rest, pay attention to warmth, prevent cold and moisture, prevent infection, regular follow-up, strengthen exercise, improve the body’s resistance to disease.