The incidence of gallbladder stones in China has reached 10%, and the admission rate of gallbladder stones accounts for about 11.5% of general surgery inpatients, and the ratio of female patients to male patients is about 2.57:1. The common clinical manifestations of gallbladder stones are: biliary colic, epigastric vague pain or swelling and discomfort, back or shoulder back swelling and discomfort, etc., or combined with some common symptoms of the digestive tract, such as decreased digestive function, bitter mouth, etc., of course, patients with severe symptoms may have other complications such as chills and fever, jaundice, severe abdominal pain, etc. Of course, patients with severe symptoms may have other complications such as chills and high fever, jaundice and severe abdominal pain. Ultrasound is the first choice for the diagnosis of gallbladder stones, and the diagnosis can be confirmed by ultrasound examination. The first choice of treatment for gallbladder stones, i.e. the “gold standard”, is laparoscopic cholecystectomy. For patients with asymptomatic gallbladder stones, that is, those found on physical examination, preventive surgery is generally not required and can be observed and followed up. However, surgery is recommended in the following cases: 1. large number of gallbladder stones, size of gallbladder stones, diameter >2-3cm or diameter <5-6mm, i.e. large stones or small stones. 2, calcification of gallbladder wall or porcelain gallbladder (porcelain gallbladder). 3.Gallbladder stones combined with gallbladder polyps. 4.Significant thickening of the gallbladder wall. 5.Gallbladder stones in pediatric patients. 6. Patients who intend to go to school or work abroad, especially to go abroad, are recommended to have early surgical treatment. 7. Women of childbearing age who intend to get pregnant and have a baby are recommended to have early surgical treatment. Several problems of gallbladder polyps, the following conditions may have the tendency of malignant transformation and require surgical treatment: 1, large gallbladder polyps, diameter > 1cm. 2, single gallbladder polyps, gallbladder polyps with wide base. 3.The gallbladder polyps gradually increase in size during regular observation, especially the short-term (within three months) growth is more obvious. 4. For gallbladder polyps over 2cm, laparoscopic surgery is not recommended, open cholecystectomy is recommended, and intraoperative rapid cryopathological examination is routinely performed. 5. Adenomatous lesions of gallbladder, which are considered as precancerous lesions of gallbladder cancer, are recommended for surgical treatment. Finally, the “gallbladder preservation” surgical treatment, “gallbladder stone retrieval surgery” caters to the psychology of most people, and the surgery is relatively simple, however, the recurrence rate of gallbladder stones is high after surgery, and the possibility of gallbladder wall lesions is not ruled out, which may lay the groundwork for the patient’s future life. The stakes are laid and a second surgery is required. Surgery is not only from physical trauma and pain, but mainly from psychological fear, because a gallbladder stone and endure two or even more surgeries, the physiological plus psychological impact on the patient is greater than the loss. If you encounter gallbladder cancer, even if your intestines are blue, there is no regret medicine to eat, it is like encountering a car accident that could have been avoided, but you have to crash into the car, what can you do.