The treatment of syphilis is generally preferred to penicillin drugs, such as clinical commonly used are aqueous penicillin, procaine penicillin, benzathine penicillin, patients who are allergic to penicillin can also choose tetracycline or erythromycin. Most syphilis can be cured, but syphilis treatment takes a long time, starting from receiving treatment, patients are usually required to continuously observe for 2-3 years, the first year after regular treatment, every 3 months need to be regularly serological review to observe the treatment of the disease. If the disease is well controlled, it will be reviewed every six months for the second and third years. If the results are normal for 3-4 times in a row during the recheck, only then can syphilis be judged as cured and the patient can stop the medication.