The main symptom of osteoporosis is pain, 70%-80% of which is manifested as pain, and it is mainly pain in the lower back. In general, osteoporosis does not appear to be afraid of cold. In addition to pain, patients may also have weakness, calf twitching or bilateral lower limb tenderness, joint pain, etc. We should pay attention to the patient’s symptoms. If the patient has cold fear or joint pain, in addition to bone density examination to exclude osteoporosis, we should also pay attention to rheumatoid and rheumatic diseases, and pay attention to appropriate calcium supplementation and vitamin D treatment in the treatment. If the patient is a postmenopausal woman or an elderly person, it is more important to actively diagnose and treat osteoporosis. Patients with osteoporosis are not afraid of cold as the main symptom, pain is the main symptom of osteoporosis and should be given sufficient attention.