Not all depressions require medication in clinical practice. According to the severity of depression, it is classified into mild depression, moderate depression and major depression. For the above three types of depression, clinical treatment methods are different: First, mild depression. Mild depression has mild symptoms and can be treated effectively through self-regulation and psychotherapy, for example, self-regulation includes exercise, establishing a reasonable life structure, sun exposure, adequate vitamin-rich fruits and vegetables, relaxation training and other related means and methods. At the same time, psychotherapy is also effective in the treatment of depression, and good results can be achieved through cognitive-behavioral therapy, psychoanalytic therapy, interpersonal therapy and other psychotherapy methods. For example, cognitive-behavioral therapy, for depressed patients, mainly through changing their poor cognition and distorted cognition, and then cognitive reconstruction to achieve the effect of improving the symptoms of depression. Secondly, for patients with moderate and severe depression, pharmacotherapy is preferred in the clinical treatment process, and pharmacotherapy is based on 5-hydroxytryptamine reuptake inhibitors, such as paroxetine, fluoxetine, sertraline, escitalopram, venlafaxine and other drugs. In the process of treatment, adequate amount and course of systematic and regular treatment are emphasized, while psychotherapy can be carried out in the recovery period of moderate and severe depression patients. The combination of the above methods can play a good treatment effect on depression patients.