The diagnosis of depression is based on medical history, clinical manifestations, and ancillary tests to determine whether the patient is suffering from depression. History taking is mainly through the patient’s own narrative, and family members’ provision. The clinical manifestations are whether the patient has depressed mood, sullenness, diminished interest, lack of interest, loss of pleasure, feeling of helplessness and hopelessness, or even some feelings of despair, or whether there is any physical discomfort, such as decreased energy, weakness, laziness, reduced activity, and whether there is any eating disorder or sleep disorder. These are some of the common clinical manifestations. The duration of these symptoms, whether they last for more than two weeks, has an impact on the patient’s daily life and social function. On the other hand, auxiliary examinations include psychological assessment, commonly used depression self-rating scale or other assessment scale, to determine whether there are these depressive moods, it is recommended that if you have the above conditions, go to a regular hospital for systematic examination and treatment in a timely manner, and seek the help of a doctor.