The presence of polycystic ovary syndrome may be associated with various emotional problems, most commonly with depression. Polycystic ovary syndrome is a common gynecological disease that affects women’s fertility because of irregular menstruation and endocrine disorders, resulting in irregular menstruation or even amenorrhea, and in severe cases, ovulation disorders. If a woman is unable to have children for a long time after marriage and has difficulty getting pregnant, she will have a lot of psychological pressure and suffer a lot of contradictions and conflicts from her family and lover, and over time, she will easily become depressed and unhappy, and will have a lot of pessimism, negative thoughts, low self-esteem and self-blame about the future, and in serious cases, she may even have negative thoughts, which may lead to depression. Therefore, the appearance of polycystic ovary syndrome accompanied by depression must be actively treated, family members more words of comfort, more tolerance and encouragement, is a very important way to treat polycystic ovary syndrome accompanied by depression problems.