Acne, or acne, that appears as a hard bulge is most often considered to be due to increased inflammation. It may be related to a variety of reasons, such as androgen production and bacterial infection, which triggers chronic folliculitis or sebaceous cysts. According to different situations, appropriate treatment measures should be taken: 1. Chronic folliculitis: i.e. recurrent folliculitis, the affected area can be disinfected with iodophor and combined with the use of immunomodulators, such as transfer factor oral solution, thymidine enteric capsules, etc. It can also be treated with topical topical fusidic acid cream and ofloxacin gel, as well as with anti-inflammatory drugs such as azithromycin dry mix suspension. In addition, it is recommended that patients visit the hospital, if it is clear that the disease is caused by diabetes and other diseases, should first actively treat the original disease; 2, sebaceous cysts: mainly due to sebaceous gland duct obstruction, resulting in sebaceous gland excretion obstruction, gradually siltation and hard bulge. Treatment is mainly based on surgical treatment. For small cysts, they can be removed surgically and antibiotic drugs can be used to control infection. For sebaceous cysts with combined infection, the infection needs to be controlled first and then surgical treatment is performed. For larger cysts, incision and drainage is required if necessary. If the cysts are stubborn, glucocorticoid injections into the lesions can also be used to help relieve symptoms quickly. In addition, patients should pay attention to cleanliness and hygiene, avoid scratching, rubbing and squeezing the affected area. Patients should also pay attention to rest, avoid staying up late, and avoid eating spicy and irritating foods such as chili, onion, leek, ginger and garlic to avoid aggravating the disease.